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Ch. 24 - Principles of DiseaseWorksheetSee all chapters
All Chapters
Ch. 1 - Introduction to Microbiology
Ch. 2 - Disproving Spontaneous Generation
Ch. 3 - Chemical Principles of Microbiology
Ch. 4 - Water
Ch. 5 - Molecules of Microbiology
Ch. 6 - Cell Membrane & Transport
Ch. 7 - Prokaryotic Cell Structures & Functions
Ch. 8 - Eukaryotic Cell Structures & Functions
Ch. 9 - Microscopes
Ch. 10 - Dynamics of Microbial Growth
Ch. 11 - Controlling Microbial Growth
Ch. 12 - Microbial Metabolism
Ch. 13 - Photosynthesis
Ch. 15 - DNA Replication
Ch. 16 - Central Dogma & Gene Regulation
Ch. 17 - Microbial Genetics
Ch. 18 - Biotechnology
Ch. 21 - Viruses, Viroids, & Prions
Ch. 22 - Innate Immunity
Ch. 23 - Adaptive Immunity
Ch. 24 - Principles of Disease
Sections
Symbiotic Relationships
The Human Microbiome
Characteristics of Infectious Disease
Stages of Infectious Disease Progression
Koch's Postulates
Molecular Koch's Postulates
Bacterial Pathogenesis
Introduction to Pathogenic Toxins
Exotoxins Cause Damage to the Host
Endotoxin Causes Damage to the Host
Exotoxins vs. Endotoxin Review
Immune Response Damage to the Host
Introduction to Avoiding Host Defense Mechanisms
1) Hide Within Host Cells
2) Avoiding Phagocytosis
3) Surviving Inside Phagocytic Cells
4) Avoiding Complement System
5) Avoiding Antibodies
Viruses Evade the Immune Response

Concept #1: Stages of Infectious Disease Progression

Practice: Times and dates of Bob’s symptoms of disease: 

  • January 7th: Bob is scratched and bitten by a stray dog.    
  • January 9th: The stray dog is found dead. Animal control finds that the dog has Yersinia pestis (bubonic plague). 
  • January 10th: Bob has fever, chills, and vomiting. 
  • January 11th: Bob is hospitalized with diarrhea & has swollen lymph nodes. 
    • Doctors find Bob is infected with Yersinia pestis and give him antibiotics. 
  • January 21st: Bob’s vitals return to normal and he is released from the hospital. 

Identify the incubation period for Bob’s case of the bubonic plague:

Practice: Times and dates of Bob’s symptoms of disease: 

  • January 7th: Bob is scratched and bitten by a stray dog.    
  • January 9th: The stray dog is found dead. Animal control finds that the dog has Yersinia pestis (bubonic plague). 
  • January 10th: Bob has fever, chills, and vomiting. 
  • January 11th: Bob is hospitalized with diarrhea & has swollen lymph nodes. 
    • Doctors find Bob is infected with Yersinia pestis and give him antibiotics. 
  • January 21st: Bob’s vitals return to normal and he is released from the hospital. 

Identify the prodromal period for Bob’s case of the bubonic plague:

Concept #2: Chronic & Latent Infection Disease Progression

Practice: Most individuals become infected with varicella zoster virus (VZV) during childhood which results in a disease commonly known as chicken pox. After the individual recovers from chicken pox the virus remains dormant in their body. This virus will commonly re-emerge when the individual reaches an advanced age and cause a disease commonly known as shingles. The shingles disease is what stage in the disease progression of the varicella zoster virus?

Practice: Individuals infected with human immunodeficiency virus (HIV) begin to show flu-like symptoms 2-4 weeks after infection. During this period, HIV is rapidly multiplying in the body. HIV will continue to slowly multiply within infected individuals for the remainder of their lives (although this can be lessened with antiretroviral therapy). HIV is an example of what type of disease?