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Ch.4 Genetic Mapping and LinkageWorksheetSee all chapters
All Chapters
Ch.1 Introduction to Genetics
Ch.2 Mendel's Laws of Inheritance
Ch.3 Extensions to Mendelian Inheritance
Ch.4 Genetic Mapping and Linkage
Ch.5 Genetics of Bacteria and Viruses
Ch.6 Chromosomal Variation
Ch.7 DNA and Chromosome Structure
Ch.8 DNA Replication
Ch.9 Mitosis and Meiosis
Ch.10 Transcription
Ch.11 Translation
Ch.12 Gene Regulation in Prokaryotes
Ch.13 Gene Regulation in Eukaryotes
Ch.14 Genetic Control of Development
Ch.15 Genomes and Genomics
Ch.16 Transposable Elements
Ch.17 Mutation, Repair, and Recombination
Ch.18 Molecular Genetic Tools
Ch.19 Cancer Genetics
Ch.20 Quantitative Genetics
Ch.21 Population Genetics
Ch.22 Evolutionary Genetics
Mapping Overview
Crossing Over and Recombinants
Mapping Genes
Trihybrid Cross
Multiple Cross Overs and Interference
Chi Square and Linkage
Mapping with Markers
Positional Cloning

Concept #1: Chi Square and Linkage

Practice: Black(B) rabbit coat colors are dominant to white(b) coat colors. Long hair (H) is dominant to short hair (h). A breeder crosses a rabbit homozygous for white, short hair with a homozygous black rabbit with long hair. The F1 is backcrossed to the rabbit with white, short hair and the following progeny are produced. Use the chi-square test to answer the following questions.

What are the expected offspring numbers if the two genes are not linked, and therefore assort independently? 

Practice: Calculate the chi-square value for the above problem. 

Practice: In this example, how many degrees of freedom should be used?

Practice: Using the appropriate chi-square value and degrees of freedom, do the coat color and hair length genes assort independently?