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Ch. 7 - Enzyme Inhibition and Regulation WorksheetSee all chapters
All Chapters
Ch. 1 - Introduction to Biochemistry
Ch. 2 - Water
Ch. 3 - Amino Acids
Ch. 4 - Protein Structure
Ch. 5 - Protein Techniques
Ch. 6 - Enzymes and Enzyme Kinetics
Ch. 7 - Enzyme Inhibition and Regulation
Ch. 8 - Protein Function
Ch. 9 - Carbohydrates
Ch. 10 - Lipids
Ch. 11 - Biological Membranes and Transport
Ch. 12 - Biosignaling
Clutch Review 1: Nucleic Acids, Lipids, & Membranes
Clutch Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Clutch Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism
Clutch Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Sections
Enzyme Inhibition
Irreversible Inhibition
Reversible Inhibition
Inhibition Constant
Degree of Inhibition
Apparent Km and Vmax
Inhibition Effects on Reaction Rate
Competitive Inhibition
Uncompetitive Inhibition
Mixed Inhibition
Noncompetitive Inhibition
Recap of Reversible Inhibition
Allosteric Regulation
Allosteric Kinetics
Allosteric Enzyme Conformations
Allosteric Effectors
Concerted (MWC) Model
Sequential (KNF) Model
Negative Feedback
Positive Feedback
Post Translational Modification
Ubiquitination
Phosphorylation
Zymogens
Learn
Next SectionRecap of Reversible Inhibition

Concept #1: Noncompetitive Inhibition

Concept #2: Noncompetitive Inhibitor Effects

Concept #3: Noncompetitive Inhibition & Michaelis-Menten-Plots

Concept #4: Noncompetitive Inhibition & Lineweaver-Burk-Plots

Practice: Indicate with an “x” which of the kinetic parameters would be altered in the presence of the given inhibitor.

Practice: What can be determined from the following Lineweaver Burk plot?

Practice: How would you expect the line on a Lineweaver-Burk plot to change if the enzyme was treated with a noncompetitive inhibitor?

Previous SectionMixed Inhibition
Next SectionRecap of Reversible Inhibition