Practice: At a CO2 partial pressure of 5 torr, the p50 value for hemoglobin is 26 torr. What is the fractional saturation when nH = 3 and pO2 = 25 torr, a typical venous oxygen partial pressure?
Concept #1: Cooperative Ligand-Binging in Allosteric Proteins
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Concept #2: The Hill Equation
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Concept #3: The Hill Equation
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Concept #4: When nH = n
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Practice: At a CO2 partial pressure of 5 torr, the p50 value for hemoglobin is 26 torr. What is the fractional saturation when nH = 3 and pO2 = 25 torr, a typical venous oxygen partial pressure?
Practice: What is Hb’s fractional saturation when p50 = 26 torr, nH = 3, and pO2 = 100 torr, a typical pO2 in the lungs?
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