Practice: Which of the following is true about allosteric enzyme conformational states?
Concept #1: Allosteric Enzyme Conformations
Concept #2: T State & R State
Concept #3: Allosteric Constant (L0)
Practice: Which of the following is true about allosteric enzyme conformational states?
Concept #4: T/R Conformations Allow for Cooperative Kinetics
Concept #5: L0 Dictates Curve in Kinetics Plots
Practice: An allosteric enzyme that follows the concerted model mechanism has a L 0 = 10,000 in the absence of substrate. A mutation in this enzyme caused the L0 to now be 1/10,000 (reciprocal to its original value). What affect does this mutation have on the reaction rate of the enzymatic reaction?
